SILYMARIN
Item # EB0280-103-10
DESCRIPTION
A drug of plant origin with hepatoprotective action. The active component
of Carsil, Silymarin stabilizes the cell membrane of the liver and
stimulates protein synthesis, which restores the functions of the damaged
cells and protects the liver parenchyma from destructive action of noxae.
MOLECULAR MASS: (Silymarin main component) 500.47
PHYSICOCHEMICAL INDICES OF THE FINISHED PRODUCT
| ¤ Appearance | amorphous powder |
| ¤ Color | yellow to yellow-brown |
| ¤ Odour | slight, specific |
| ¤ Solubility | |
 in water |
practically insoluble |
| in dioxane |
soluble |
| in methanol |
slightly soluble |
| ¤ Tanning substances | |
| content (mg/g) |
not more than 100.00 |
| ¤ Content of substances extracted | |
| in petroleum ether (mg/g) |
not more than 10.00 |
| ¤ Sulphate ash (mg/g) | not more than 5.0 |
| ¤ Heavy metals (mg/g) | not more than 20.0 |
| ¤ Water content (mg/g) | not more than 60.0 |
| ¤ Silymarin content calculated as dry substance (%) | not less than 65.0 |
| ¤ Total content of silybine and isosilybine (%) | not less than 25.0 |
| ¤ Total content of silycristine and silydianine (%) | not less than 12.0 |
| ¤ Residual solvents content (mg/g) | |
| in methanol |
not more than 1.0 |
| in hexane |
not more than 1.5 |
| ¤ Microbial content | |
| total microorganisms (number/g) |
not more than 10-3 |
| moulds and yeast (number/g) |
not more than 10-2 |
| Enterobacteriaceae |
|
| Ps. aeruginosa, St. aureus |
not allowed |
| ¤ Supplied | The substance is filled in double polyethilene bags of 25 kg and 40 kg and place in cardboard barrels. |
| ¤ Quality | Bulgarian standard |
| ¤ Expiry term | 3 years |
| ¤ Medicinal form and package | Carsil s.c. tablets, original Bulgarian drug of 35 mg in packs of 80. |
| ¤ Similar brands | Legalon |