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Carsil ® (Silymarin)  
Carsil (Silymarin) Introduction
Carsil (Silymarin) a result of a natural product
Carsil (Silymarin) mechanism of action
Carsil (Silymarin) pharmacological studies
Carsil (Silymarin) pharmacokinetic studies
Tolerance to Carsil (Silymarin), toxicological studies
Clinical use of Carsil (Silymarin)
Carsil (Silymarin) in chronic liver diseases (CLD)
Carsil indications
Carsil adverse reactions
Carsil contraindications
Administration and posology
Storage
Table of contents
Package insert
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Order online  

Silymarin substance (kg)

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carsil home / supplements

 
 
  Carsil®

SILYMARIN
Item # EB0280-103-10

DESCRIPTION
A drug of plant origin with hepatoprotective action. The active component of Carsil, Silymarin stabilizes the cell membrane of the liver and stimulates protein synthesis, which restores the functions of the damaged cells and protects the liver parenchyma from destructive action of noxae.

MOLECULAR MASS: (Silymarin main component) 500.47

PHYSICOCHEMICAL INDICES OF THE FINISHED PRODUCT

¤ Appearance amorphous powder
¤ Color yellow to yellow-brown
¤ Odour slight, specific
¤ Solubility
in water practically insoluble
in dioxane soluble
in methanol slightly soluble
¤ Tanning substances
content (mg/g) not more than 100.00
¤ Content of substances extracted
in petroleum ether (mg/g) not more than 10.00
¤ Sulphate ash (mg/g) not more than 5.0
¤ Heavy metals (mg/g) not more than 20.0
¤ Water content (mg/g) not more than 60.0
¤ Silymarin content calculated as dry substance (%) not less than 65.0
¤ Total content of silybine and isosilybine (%) not less than 25.0
¤ Total content of silycristine and silydianine (%) not less than 12.0
¤ Residual solvents content (mg/g)
in methanol not more than 1.0
in hexane not more than 1.5
¤ Microbial content
total microorganisms (number/g) not more than 10-3
moulds and yeast (number/g) not more than 10-2
Enterobacteriaceae
Ps. aeruginosa, St. aureus not allowed
¤ Supplied The substance is filled in double polyethilene bags of  25 kg and 40 kg and place in cardboard barrels.
¤ Quality Bulgarian standard
¤ Expiry term 3 years
¤ Medicinal form and package Carsil s.c. tablets, original Bulgarian drug of 35 mg in packs of 80.
¤ Similar brands Legalon

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